The church of St Michael and All Angels stands in the centre of the village of Weyhill, which straddles the busy A342 in the parish of Penton Grafton, just W of Andover. Weyhill was the site of an important Michaelmas fair, which was held on a site W of the church from the early 13thc., if not earlier.

The church has a largely Victorian appearance. The walls are of flint with decorative red brick detailing and ashlar quoins. The walls are roofed with slate (nave) or red tiles (aisle and chancel). The building comprises a chancel with a N vestry, a N transept, a nave with a S aisle and S porch, and a W bell turret. Inside, the chancel arch dates from the 12thc.

An 11thc. grave slab built into the W wall of the N vestry has been recorded by the Corpus of Anglo-Saxon Stone Sculpture.

The church is mentioned in the Domesday Survey of 1086. The church and manor of Penton Grafton were then held by the Abbey of Grestain, near Honfleur in Normandy. They seem to have been retained by the Abbey until the sequestration of alien houses in the 14thc.

The N transept was added in 1827. The end bay was used as a vestry until the new vestry was erected on the N side of the chancel (between 1863 and 1873). The architect J. H. Hakewill added the S aisle and S porch, and restored the nave, in 1862-63 (Hampshire Chronicle, 19 September 1863, 5). He may also have added the vestry. The chancel was restored in 1879 (Hampshire Advertiser, 15 November 1879, 7). The bell turret was built in 1907 by Cancellor.

The chancel arch is dated to c.1180 by Bullen et al., 2010, 546.