The foundation date is not recorded, but the surviving capitals suggest a date in the 1170s or ‘80s. The founder was probably one Adam Walder, as in an inquisition of 1245 it was recorded that the brethren and sisters of the house were to pray for his soul, and also to distribute bread to the poor every year on Lady Day. The earliest notice of the hospital is a record of a lawsuit between the master, Gilbert, and Richard of Rouen concerning land in High Wycombe in 1236. In 1239 the brethren were granted the right to hold an annual fair on the feast of the translation of St Thomas Becket (7 July). After the Suppression of Chantries act of 1547 the house was sold to the mayor and burgesses and converted into a grammar school.