St Wilfrid's has a long nave and chancel, continuous inside and out with no chancel arch but the division marked by a step. N and S aisles occupy the five bays of the nave and two bays of the chancel; a short aisleless section of chancel at the E end is raised for the main altar. At the W end is a tower, and a transeptal vestry has been added to the N chancel aisle. The earliest part of the fabric is the remnant of a corbel table high in the N wall of the S aisle. This indicates an early 12thc. aisleless church. In 1334 the Boydell Chapel was added alongside this nave on the S side, and features of this remain in the S windows and some of the glass. In 1525-39 there was a major rebuilding involving the construction of both arcades and aisles, and the W tower. The clerestorey was added in 1833, and remodelled in the major restoration of 1874 by Paley and Austin. The N vestry also dates from this restoration. The font and the corbels in the S aisle are described below.

In 1086 Grappenhall was among the lands of Earl Hugh of Chester. It was held from him by Osbern fitzTesso, and from Osbern by Edward. No church was mentioned at that time.