Greywell is not recorded by that name in the Domesday Survey, where it was probably included under Odiham. The earliest mention of the manor is in 1167, when it was held by one Richer (see Willoughby). Odiham was held by Earl Harold before the Conquest and by King William in demesne in 1086, when it was a vast manor of 80 hides. In 1204 King John granted the issues of the manor of Greywell to Alan Basset, and after Alan's death in 1233, Henry III granted the estate, then described as 'late of Gilbert de Aquila', to Gilbert Marshal, Earl of Pembroke. The Earl later granted Greywell to his niece Isabel on her marriage to Alan Basset's son Gilbert. For the later medieval history of the manor, see the Victoria County History.
The church was formerly a chapelry of Odiham, and the vicar of Odiham still kept a priest there at the Reformation.