Twyford is a village in the South Derbyshire district, on the River Trent on the southern otskirts of Derby. The church is on a lane runnning alongside the river to the S of the village centre. It consists of a nave, chancel and a small tower and spire at the west end. The church is predominantly of the 14thc, although there is a Norman chancel arch and the lower stage of the tower has lancet windows dating from the early-13^th century. The nave is of faced with brick, - it resembles the style of work at Trusley church, Derbyshire. The only Romanesque feature is the chancel arch.

Twyford and Stenson were held by Leofric before the Conquest, and by Henry de Ferrers in 1086. It was assessed at 4 carucates.

Both the list description and Hartwell (but not Pevsner 1953) mistakenly describe dogtooth on the chancel arch imposts. It is chip-carving, which is rather different and at least half a century earlier. The chevron is a richer version of tat on the S doorway at Kedleston.