The church is primarily of the 13thc. with a five-bay nave arcade and N and S aisles which flank the W tower. The S porch, S transept, and chancel are of the 14thc. Romanesque elements consist of the font and the W tower arches leading into the nave and side aisles.

Under the listing of the land of Guy of Craon, the Domesday Survey records the existence of a church and a priest in Frampton in 1086. The inscription on the modern base of the font reads: '+ TO THE GLORY OF GOD / AND IN FILIAL MEMORYOF / ELIZABETH ANNA DR OF THO TUNNARD ESQR / WIFE TO REVD CHARLES MOORE / BAPD 12 JANY 1795 DEC D 29 NOVR 1837 / THIS FONT / THE SOLE RELIC OF AN EARLIER CHURCH / WAS HERE ERECTED A.D. 1889 / R.I.P.'

In the nave wall directly behind the W respond of the S arcade there is an opening with a pointed arch above it; the lower part of the opening is now in-filled with new ashlar. An inscription here reads: 'The font taken out of this arch and pillar and restored – A.D. 1862 +'. The local church notes further mention that 'for many years the font was housed in the southeast corner of the tower, until such time as it became necessary to move it to the southwest corner, to enable further strengthening of the tower support. It was moved to its present more practical location, in the Lady Chapel [i.e. S transept], in March 2000, as part of a Millennium project.'

The embedding of the font into the wall behind the W respond of the S arcade is similar to the treatment of the font at Crowland Abbey.